A systematic review of the effectiveness of interventions for managing childhood nocturnal enuresis

NHS Centre for Reviews and Dissemination
Record ID 31999008340
Authors' objectives:

This review aims to assess and compare the effectiveness of interventions for treating bedwetting (nocturnal enuresis).

Authors' recommendations: The use of enuresis alarms is over 13 times more likely to help children achieve at least 14 consecutive dry nights compared to no treatment. This behavioural treatment can take several months to work fully. The drugs imipramine and desmopressin can reduce the number of wet nights per week quite quickly. However, the effect is not as sustained as enuresis alarms and both have potentially serious side effects. Desmopressin is much more expensive but no more effective than imipramine. Other commonly used forms of management such as star charts and rewards, fluid deprivation and lifting have not been reliably evaluated.
Authors' methods: Systematic review
Project Status: Completed
Year Published: 1997
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: England
MeSH Terms
  • Adolescent
  • Child
  • Child, Preschool
  • Costs and Cost Analysis
  • Enuresis
Organisation Name: University of York
Contact Address: University of York, York, Y01 5DD, United Kingdom. Tel: +44 1904 321040, Fax: +44 1904 321041,
Contact Name: crd@york.ac.uk
Contact Email: crd@york.ac.uk
Copyright: Centre for Reviews and Dissemination
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.