Universal leukorreduction. A systematic review of the literature and an economic assessment

Jose Aguado Romeo M, Villegas Portero R, Marquez Pelaez S, Corbacho Martin B, Antonio Navarro Caballero J
Record ID 32007000461
Authors' objectives:

To assess the efficacy of universal leukorreduction of cellular components (erythrocyte and platelet concentrates) in terms of reducing the rate of complications related to allogeneic leukocyte transfusion, compared with leukocytic layer removal and/or selective leukorreduction or other techniques; and to estimate the economic impact of a potential change in strategy.

Authors' recommendations: There is no new scientific evidence to justify performing ULR, nor advantages over leukorreduction using other methods, such as removal of the leukocyte layer and/or selective leukorreduction.
Authors' methods: Systematic review
Project Status: Completed
Year Published: 2007
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Spain
MeSH Terms
  • Blood Transfusion
  • Leukocyte Reduction Procedures
  • Systematic Review
Organisation Name: Andalusian Health Technology Assessment Area
Contact Address: Area de Evaluacion de Tecnologias Sanitarias Sanitarias de Andalucia (AETSA) Avda. InnovaciĆ³n, s/n Edificio Arena 1. Sevilla (Spain) Tel. +34 955 006 309
Contact Name: aetsa.csalud@juntadeandalucia.es
Contact Email: aetsa.csalud@juntadeandalucia.es
Copyright: Andalusian Agency for Health Technology Assessment (AETSA)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.