Genetic testing for susceptibility to hereditary nonpolyposis colorectal cancer
Record ID 32006000928
English
Authors' objectives:
In families with suspected or clinically diagnosed hereditary nonpolyposis colorectal cancer (HNPCC), genetic testing for mutations in one of several mismatch repair (MMR) genes is used to determine whether an individual has an increased risk for colorectal cancer or other HNPCC-associated cancers, improving cancer risk assessment in these individuals and families. Testing may also include microsatellite instability (MSI) analysis and/or immunohistochemical staining of the tumor tissue of an affected family member as initial screen(s) before germline mutation testing is performed.
Authors' methods:
Review
Details
Project Status:
Completed
Year Published:
2005
URL for published report:
http://www.hayesinc.com/hayes/crd/?crd=2211
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
United States
MeSH Terms
- Colorectal Neoplasms, Hereditary Nonpolyposis
Contact
Organisation Name:
HAYES, Inc.
Contact Address:
157 S. Broad Street, Suite 200, Lansdale, PA 19446, USA. Tel: 215 855 0615; Fax: 215 855 5218
Contact Name:
saleinfo@hayesinc.com
Contact Email:
saleinfo@hayesinc.com
Copyright:
HAYES, Inc.
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.