Authors' objectives:

This overview looks at the clinical and cost effectiveness of computed tomography (CT) and magnetic resonance imaging (MRI) for selected clinical disorders. It is based on two Technology Reports commissioned by CADTH: Foerster V, Murtagh J, Lentle BC, Wood RJ, Reed MH, Husereau D, Mensinkai S. CT and MRI for selected clinical disorders: a systematic review of clinical systematic reviews. Ottawa: Canadian Coordinating Office for Health Technology Assessment; 2005. Technology report no. 59 and Murtagh J, Warburton RN, Foerster V, Lentle BC, Wood RJ, Mensinkai S, Husereau D. CT and MRI for selected clinical disorders: a systematic review of economic evaluations. Ottawa: Canadian Agency for Drugs and Technologies in Health; 2006. Technology report no. 68.

Authors' recommendations: Implications for Decision Making Evidence for use of CT in investigation of stroke is promising. The most compelling evidence of clinical and cost effectiveness suggested that CT scanning within 48 hours of presentation for stroke patients has the potential to improve quality-adjusted life-years, and offset the costs of in-patient care. Some CT and MRI uses are still investigational. No economic evidence was found supporting use of these technologies in coronary artery disease, headaches, and seizures. No clinical or economic evidence was found for cerebral arteriovenous malformations (AVMs) and urolithiasis screening. Less compelling evidence was found for other conditions. Decisions to use these technologies for the remaining clinical conditions appears to be based solely on demonstrated diagnostic performance or clinical opinion, not on published evidence. Evidenced-based decisions require an updated review. CT and MRI technologies have advanced rapidly. Findings from the identified SRs and economic evaluations may not be sufficiently contemporary in some instances to be useful to clinicians and decision makers.

Authors' methods: Overview

Project Status: Completed

URL for project: http://www.cadth.ca/

Year Published: 2006

English language abstract: An English language summary is available

Publication Type: Not Assigned

Country: Canada

Organisation Name: Canadian Agency for Drugs and Technologies in Health

Contact Address: 600-865 Carling Avenue, Ottawa, ON K1S 5S8 Canada. Tel: +1 613 226 2553; Fax: +1 613 226 5392;

Contact Name: requests@cadth.ca

Contact Email: requests@cadth.ca

Copyright: Canadian Agency for Drugs and Technologies in Health (CADTH)