Living-donor lung transplantation for end-stage lung disease
National Institute for Health and Clinical Excellence
Record ID 32006000718
English
Authors' objectives:
This study aims to assess the current evidence on living-donor lung transplantation for end-stage lung disease.
Authors' recommendations:
1 Guidance
1.1 Current evidence on the efficacy of living-donor lung transplantation for end-stage lung disease and its safety profile for suitable recipients appears adequate to support the use of this procedure.
1.2 The procedure should only be used in selected patients who would otherwise die.
1.3 However, limited evidence suggests that living-donor lung transplantation for end-stage lung disease carries a significant risk of morbidity for donors. Therefore clinicians wishing to undertake this procedure should take the following actions. - Inform the clinical governance leads in their Trusts. - Ensure that donors receive thorough physical and psychological screening, and counselling about the morbidity associated with this procedure. They should also be provided with clear written information. In addition, use of the Institute's Information for the public is recommended (available from www.nice.org.uk/IPG170publicinfo). - Audit and review clinical outcomes of all people donating lungs for transplantation.
1.4 Living-donor lung transplantation for end-stage lung disease should only be performed in specialist centres in the context of a multidisciplinary team. Donor lungs should be harvested by specialist thoracic surgeons.
1.5 Clinicians should enter all donors and recipients into the UK National Audit of Intrathoracic Transplantation (<url>www.rcseng.ac.uk/research/ceu/projects/proj_intrathoracic.html</ur l>).
Authors' methods:
Overview
Details
Project Status:
Completed
URL for project:
http://www.nice.org.uk/page.aspx?o=ip_292
Year Published:
2006
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
England
MeSH Terms
- Living Donors
- Lung Diseases
- Lung Transplantation
Contact
Organisation Name:
National Institute for Health and Care Excellence
Contact Address:
Level 1A, City Tower, Piccadilly Plaza, Manchester, M1 4BT
Contact Name:
nice@nice.nhs.uk
Contact Email:
nice@nice.nhs.uk
Copyright:
National Institute for Health and Clinical Excellence (NICE)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.