Authors' objectives:

This study aims to assess the current evidence on mosaicplasty for knee cartilage defects.

Authors' recommendations: 1 Guidance 1.1 Current evidence suggests that there are no major safety concerns associated with mosaicplasty for knee cartilage defects. There is some evidence of short-term efficacy, but data on long-term efficacy are inadequate. In view of the uncertainties about the efficacy of the procedure, it should not be used without special arrangements for consent and audit or research. 1.2 Clinicians wishing to undertake mosaicplasty for knee cartilage defects should take the following actions. - Inform the clinical governance leads in their Trusts. - Ensure that patients understand the uncertainty about the procedure's efficacy and the options for alternative treatments. They should provide them with clear written information. In addition, use of the Institute's Information for the public is recommended (available from www.nice.org.uk/IPG162publicinfo). - Audit and review clinical outcomes of all patients having mosaicplasty for knee cartilage defects. The Institute may review the procedure upon publication of further evidence.

Authors' methods: Overview

Project Status: Completed

URL for project: http://www.nice.org.uk/page.aspx?o=297811

Year Published: 2006

English language abstract: An English language summary is available

Publication Type: Not Assigned

Country: England

Organisation Name: National Institute for Health and Care Excellence

Contact Address: Level 1A, City Tower, Piccadilly Plaza, Manchester, M1 4BT

Contact Name: nice@nice.nhs.uk

Contact Email: nice@nice.nhs.uk

Copyright: National Institute for Health and Clinical Excellence (NICE)