[Efficacy and safety of 123I-ioflupane (DaTSCAN) in the diagnosis of parkinsonian syndromes]
Ruano-Ravina A
Record ID 32006000213
Spanish
Authors' objectives:
The aim of this study was to study the efficacy and safety of DaTSCAN in diagnosis of presynaptic Parkinsonian Syndromes.
Authors' results and conclusions:
The studies indicated that patients with presynaptic Parkinsonian Syndromes or Parkinson's disease registered a lower uptake of the radiopharmaceutical agent, observable as a less intense image or asymmetric uptake in the gammagraph (radiograph). The imaging test often led to changes in patient management. No adverse effects of the radiopharmaceutical agents were detected.
Authors' recommendations:
Gammagraphy with Ioflupane is a useful test for diagnosis of Parkinson's disease or Parkinsonian Syndromes in the early stages, and enables Parkinson's disease to be differentiated from essential tremor in most cases, but not from other illnesses such as multisystemic atrophy or progressive supranuclear paralysis. A normal image with Ioflupane is not indicative of absence of disease. Gammagraphy with Ioflupane is a safe technique.
Authors' methods:
Systematic review
Details
Project Status:
Completed
Year Published:
2005
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
Spain
MeSH Terms
- Radiopharmaceuticals
- Corpus Striatum
- Essential Tremor
- Parkinsonian Disorders
Contact
Organisation Name:
Scientific Advice Unit, avalia-t; The Galician Health Knowledge Agency (ACIS)
Contact Address:
Conselleria de Sanidade, Xunta de Galicia, San Lazaro s/n 15781 Santiago de Compostela, Spain. Tel: 34 981 541831; Fax: 34 981 542854;
Contact Name:
avalia-t@sergas.es
Contact Email:
avalia-t@sergas.es
Copyright:
Galician Agency for Health Technology Assessment (AVALIA-T)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.