The use of cardiac resynchronization therapy (CRT) for heart failure

NHS Quality Improvement Scotland
Record ID 32005001414
Authors' recommendations: There is evidence from randomised controlled trials that cardiac resynchronisation therapy (CRT or biventricular pacing) with or without a combined implantable cardioverter defibrillator (CRT/D) improves exercise tolerance, symptoms and quality of life and reduces the number of hospitalisations for heart failure in appropriately selected patients.Randomised controlled trials of CRT or CRT/D have demonstrated a reduction in all cause mortality compared to optimal medical therapy (OMT).The procedure is technically challenging with left ventricular lead implantation problems reported in 10% of patients. Serious complications occur rarely.An economic model suggests that the substantial costs of implantation and follow up can be recouped as a result of cost savings from averted heart failure related hospital admissions. Costeffectiveness analysis has indicated uncertainty in the incremental cost per QALY.
Project Status: Completed
Year Published: 2005
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Scotland
MeSH Terms
  • Cardiac Pacing, Artificial
  • Heart Failure
Organisation Name: Quality Improvement Scotland
Contact Address: Delta House, 50 West Nile Street Glasgow G1 2NP Scotland United Kingdom Tel: +44 141 225 6988; Fax: +44 141 221 3262
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