The 1997 guideline from the Danish National Board of Health recommends that a maximum of two fresh embryos should be transferred in the same treatment. The couple should also be involved in the decision-making process and therefore needs to receive the necessary information. The purpose of the guideline is to minimize the number of transferred embryos and at the same time ensure that the treatment meets the couples' desire of having a child.

The Danish Council of Ethics and the Danish Ministry of the Interior and Health have asked for more studies concerning consequences of different IVF-strategies to be able to improve the basis for decision-making.

This HTA-project contributes with the information in demand by discussing the consequences of implementing an obligatory single embryo transfer (SET) policy versus optional two embryo transfer in Denmark. The focus is on consequences for pregnancy rates, the couples preferences and knowledge and on economical and organisational aspects.