Authors' objectives:

This study aims to summarise the currently available evidence on NIOX MINO airway inflammation monitor for the diagnosis and monitoring of asthma.

Authors' recommendations: NIOX MINO is a new, smaller, portable airway inflammation monitor based on theestablished NIOX monitoring system, which detects and measures levels of nitric oxide (NO) in exhaled breath. NIOX MINO costs a fraction of the original NIOX system and does not require regular calibration. It has already been shown that fractional concentrations of exhaled NO (FENO) are increased in patients with airway inflammation (such as asthma and chronic obstructive pulmonary disease), and that FENO levels decrease after corticosteroid, NO synthase inhibitor use or other anti-inflammatory therapies. The original NIOX system has been investigated in several studies and shown to be a reliable and repeatable method for monitoring exhaled NO levels. The new NIOX MINO system has been shown to be equally as reliable and repeatable as the original system.

Authors' methods: Overview

Project Status: Completed

Year Published: 2005

URL for published report: http://www.hsric.nihr.ac.uk/search

English language abstract: An English language summary is available

Publication Type: Not Assigned

Country: England, United Kingdom

Organisation Name: NIHR Horizon Scanning Centre

Contact Address: The NIHR Horizon Scanning Centre, Department of Public Health, Epidemiology, and Biostatistics, School of Health and Population Sciences, University of Birmingham, 90 Vincent Drive, Edgbaston, Birmingham, B15 2SP. United Kingdom. Tel: +44 121 414 7831, Fax: +44 121 2269

Contact Name: c.packer@bham.ac.uk

Contact Email: c.packer@bham.ac.uk

Copyright: NIHR Horizon Scanning Centre (NIHR HSC)