Intrathecal baclofen pump for spasticity: an evidence-based analysis

Medical Advisory Secretariat
Record ID 32005001142
English
Authors' objectives:

This study reviews the literature to assess the effectiveness and cost-effectiveness of intrathecal baclofen to treat patients who have intractable spasticity uncontrolled by drug therapy, or who experience intolerable side effects to oral baclofen.

Authors' recommendations: Level 2 evidence supports the effectiveness of intrathecal baclofen infusion for the short-term reduction of severe spasticity in patients who are unresponsive or cannot tolerate oral baclofen. Level 3 evidence supports the effectiveness of intrathecal baclofen for the long-term reduction of severe spasticity in patients who are unresponsive or cannot tolerate oral baclofen. Level 4 qualitative evidence demonstrates functional improvement for patients who are unresponsive or cannot tolerate oral baclofen. Intrathecal baclofen is cost-effective with costs which may or may not be avoided in the Ontario health system. True functional use remains to be determined.
Authors' methods: Systematic review
Details
Project Status: Completed
Year Published: 2005
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Canada
MeSH Terms
  • Baclofen
  • Brain Injuries
  • Cerebral Palsy
  • Infusion Pumps, Implantable
  • Multiple Sclerosis
  • Muscle Relaxants, Central
  • Muscle Spasticity
  • Spinal Cord Injuries
Contact
Organisation Name: Medical Advisory Secretariat
Contact Address: Medical Advisory Secretariat, 20 Dundas Street West, 10th Floor, Toronto, ON M5G 2N6 CANADA. Tel: 416-314-1092l; Fax: 416-325-2364;
Contact Name: MASinfo.moh@ontario.ca
Contact Email: MASinfo.moh@ontario.ca
Copyright: Medical Advisory Secretariat, Ontario Ministry of Health and Long-Term Care
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.