A multicentre randomised controlled trial of the use of continuous positive airway pressure and non-invasive positive pressure ventilation in the early treatment of patients presenting to the emergency department with severe acute cardiogenic pulmonary oedema: the 3CPO Trial

Gray AJ, Goodacre S, Newby DE, Masson MA, Sampson F, Dixon S, Crane S, Elliott M, Nicholl J
Record ID 32005001007
English
Authors' objectives:

To determine whether non-invasive ventilation reduces mortality and whether there are important differences in outcome by treatment modality.

Authors' recommendations: Study found that non-invasive ventilatory support delivered by either continuous positive airway pressure or non-invasive positive pressure ventilation safely provides earlier improvement and resolution of breathlessness, respiratory distress and metabolic abnormality in patients with severe acute cardiogenic pulmonary oedema
Details
Project Status: Completed
URL for project: http://www.hta.ac.uk/1338
Year Published: 2009
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: England, United Kingdom
MeSH Terms
  • Acute Disease
  • Aged
  • Aged, 80 and over
  • Cost-Benefit Analysis
  • Emergency Service, Hospital
  • Intubation, Intratracheal
  • Male
  • Middle Aged
  • Oxygen Inhalation Therapy
  • Quality-Adjusted Life Years
  • Survival Analysis
  • Continuous Positive Airway Pressure
  • Heart Diseases
  • Myocardial Infarction
  • Positive-Pressure Respiration
  • Pulmonary Edema
Contact
Organisation Name: NIHR Health Technology Assessment programme
Contact Address: NIHR Journals Library, National Institute for Health and Care Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK
Contact Name: journals.library@nihr.ac.uk
Contact Email: journals.library@nihr.ac.uk
Copyright: 2009 Queen's Printer and Controller of HMSO
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