Antenatal screening for haemoglobinopathies in primary care: a cohort study and cluster randomised trial to inform a simulation model. The Screening for Haemoglobinopathies in First Trimester (SHIFT) trial
Dormandy E, Bryan S, Gulliford MC, Roberts TE, Ades AE, Calnan M, Atkin K, Karnon J, Barton PM, Logan J, Kavalier F, Harris HJ, Johnston TA, Anionwu EN, Davis V, Brown K, Juarez-Garcia A, Tsianakas V, Marteau TM
Record ID 32005000948
English
Authors' recommendations:
In areas with high prevalence, offering antenatal SCT screening as part of pregnancy-confirmation consultations in primary care increases the proportion of women screened before 10 weeks (70 days). However, it is important to note that the majority of women remain unscreened at this gestational age, raising the question of whether this is the most effective model for screening. There is no evidence to support the utility of offering screening to fathers at the same time as women are offered screening. Additional resources may be required to offer screening to women as part of pregnancy-confirmation consultations in primary care. Whether this is an efficient and fair use of resource will depend upon the values attached to early screening.
There is a need to improve existing services to reduce the delay between offer of screening and carrying out the test and to improve poor levels of knowledge about the conditions and the screening process.
Details
Project Status:
Completed
URL for project:
http://www.hta.ac.uk/1401
Year Published:
2010
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
England, United Kingdom
MeSH Terms
- Comparative Study
- Family Practice
- Female
- Pregnancy
- Anemia, Sickle Cell
- Pregnancy Complications, Hematologic
- Prenatal Diagnosis
- Thalassemia
Contact
Organisation Name:
NIHR Health Technology Assessment programme
Contact Address:
NIHR Journals Library, National Institute for Health and Care Research, Evaluation, Trials and Studies Coordinating Centre, Alpha House, University of Southampton Science Park, Southampton SO16 7NS, UK
Contact Name:
journals.library@nihr.ac.uk
Contact Email:
journals.library@nihr.ac.uk
Copyright:
2010 Queen's Printer and Controller of HMSO
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.