Tridimensional radiotherapy for breast cancer

Pichon Riviere A, Augustovski F, Cernadas C, Ferrante D, Regueiro A, Garcia Marti S
Record ID 32005000645
Authors' objectives:

The aim of this report is to evaluate tridimensional radiotherapy for breast cancer

Authors' results and conclusions: In the last five years, many series of breast cancer patients treated with tridimensional conformal radiotherapy or most recently intensity modulated radiation therapy (IMRT) have been reported. The studies, in general, included patients with breast cancer in early stages (up to E II, TNM classification). However, the studies were mainly based on dosimeter planning or the comparison of the dose received per organs at risk, without reporting prospective relevant clinical results about the therapeutic efficacy and toxicity.
Authors' recommendations: It is important to point out that the scientific evidence that suggests that both tridimensional conformal radiotherapy and IMRT can be of benefit to minimize normal tissue structure involvement and to contribute to a lower toxicity, preserving or improving the therapeutic efficacy, is still limited and of poor quality. More prospective, comparative clinical trials which evaluate relevant clinical results (such as mortality, disease-free survival, acute and immediate toxicity) must be carried out to assess its relative efficacy and cost-effectiveness in relation to bidimensional radiotherapy.
Authors' methods: Overview
Project Status: Completed
URL for project:
Year Published: 2004
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Argentina
MeSH Terms
  • Female
  • Radiation Tolerance
  • Radiotherapy Dosage
  • Breast Neoplasms
  • Radiotherapy, Conformal
Organisation Name: Institute for Clinical Effectiveness and Health Policy
Contact Address: Dr. Emilio Ravignani 2024, Buenos Aires - Argentina, C1414 CABA
Contact Name:
Contact Email:
Copyright: Institute for Clinical Effectiveness and Health Policy (IECS)
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