Transpupillary thermotherapy

Cernadas C, Pichon Riviere A, Augustovski F
Record ID 32005000631
Authors' objectives:

This study examines the use of Transpupillary Thermotherapy (TTT)

Authors' results and conclusions: Bibliographical analysis shows that the most common application of TTT is on the following pathologies: choroidal melanoma, vascular malformations (choroidal hemangioma), age-related macular degeneration as a result of choroidal neovascularization and retinoblastoma.
Authors' recomendations: There is not enough evidence to support the use of TTT in Benign Vascular Malformations and in Age-related Macular Degenerations as a result of Choroidal Neovascularization. In Choroidal Melanoma, the indication of TTT as single treatment would apply to those patients with an apical height of up to 4mm and who do not show the following exclusion criteria: pupil unable to be adequately dilated; peripherically-located tumor non visible in its full extension with laser contact lenses and subretinal fluid more than 3 mm. TTT would be indicated as a therapy combined with brachytherapy in those tumors up to 8mm in apical height. In Retinoblastoma, the indication of TTT would apply to small tumors with no subretinal seeding and isolated vitreous and in moderate-size tumors (up to 3mm diameter) combined with chemotherapy.
Authors' methods: Overview
Project Status: Completed
URL for project:
Year Published: 2003
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Argentina
MeSH Terms
  • Hyperthermia, Induced
  • Choroidal Neovascularization
  • Macular Degeneration
  • Retinal Diseases
Organisation Name: Institute for Clinical Effectiveness and Health Policy
Contact Address: Dr. Emilio Ravignani 2024, Buenos Aires - Argentina, C1414 CABA
Contact Name:
Contact Email:
Copyright: Institute for Clinical Effectiveness and Health Policy (IECS)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.