The use of autologous chondrocyte implantation for the treatment of cartilage defects in knee joints

National Institute for Clinical Excellence
Record ID 32005000326
English
Authors' objectives:

To provide guidance on the use of autologous chondrocyte implantation for the treatment of cartilage defects in knee joints. This guidance replaces Technology Appraisal Guidance No. 16 issued in December 2000.

Authors' recommendations: The review and re-appraisal of the use of autologous chondrocyte implantation (ACI) for the treatment of cartilage defects in knee joints has resulted in modifications to the guidance. Specifically: - the recommendation that ACI should not be used for routine primary treatment has been expanded to include all treatment levels - the recommendation on the use of ACI in clinical trials has been revised to recommend that all patients receiving ACI should be enrolled in ongoing or new clinical studies - a recommendation has been made that patients should be fully informed of the uncertainties about the long-term effectiveness and the potential adverse effects of this procedure.
Authors' methods: Systematic review
Details
Project Status: Completed
Year Published: 2005
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: England, United Kingdom
MeSH Terms
  • Cartilage
  • Chondrocytes
  • Knee
  • Knee Injuries
  • Knee Joint
  • Transplantation
Contact
Organisation Name: National Institute for Clinical Excellence
Contact Address: MidCity Place, 71 High Holborn, London WC1V 6NA, UK. Tel: +44 020 7067 5800; Fax: +44 020 7067 5801
Contact Name: nice@nice.nhs.uk
Contact Email: nice@nice.nhs.uk
Copyright: National Institute for Clinical Excellence (NICE)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.