The LightCycler Staphylococcus and MRSA detection kits for methicillin-resistant Staphylococcus aureus (MRSA) - horizon scanning review
NHSC
Record ID 32004000883
English
Authors' objectives:
This study aims to summarise the currently available evidence on the LightCycler Staphylococcus and MRSA detection kits for methicillin-resistant Staphylococcus aureus (MRSA).
Authors' recommendations:
The LightCycler Staphylococcus and the LightCycler MRSA detection kits are 2 real-time polymerase chain reaction (PCR) assays for patients suspected of having a methicillin-resistant S. aureus (MRSA) infection or being a carrier of the organism. After sample preparation, up to 3 hours are required on the LightCycler real-time PCR instrument. Evidence in abstract form suggests that these kits can be used to identify MRSA-positive samples after an overnight broth step or direct from nasal swabs. Results using the LightCycler kits for mixed samples containing Staphylococcus aureus, coagulase-negative Staphylococci (CoNS) and mecA will be equivocal and therefore further conventional testing will be required. Further data on analytical and clinical utility would be required before a full assessment could be made.
Authors' methods:
Overview
Details
Project Status:
Completed
Year Published:
2004
URL for published report:
http://www.psy-flow.com/sites/psy-flow/files/docs/flow.pdf
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
England, United Kingdom
MeSH Terms
- Methicillin Resistance
- Polymerase Chain Reaction
- Staphylococcal Infections
- Staphylococcus aureus
Contact
Organisation Name:
NIHR Horizon Scanning Centre
Contact Address:
The NIHR Horizon Scanning Centre, Department of Public Health, Epidemiology, and Biostatistics, School of Health and Population Sciences, University of Birmingham, 90 Vincent Drive, Edgbaston, Birmingham, B15 2SP. United Kingdom. Tel: +44 121 414 7831, Fax: +44 121 2269
Contact Name:
c.packer@bham.ac.uk
Contact Email:
c.packer@bham.ac.uk
Copyright:
National Horizon Scanning Centre (NHSC)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.