Outpatient parenteral antibiotic therapy

CDA-AMC
Record ID 32018016004
English
Authors' objectives: Outpatient parenteral antimicrobial therapy (OPAT) is a treatment option that allows patients to receive IV antimicrobials outside of the hospital setting. It is offered to patients who are well enough to leave the hospital but still require antimicrobial therapy. There are 3 main delivery models of OPAT — infusion centres, skilled nursing facilities, and home-based administration. OPAT has the potential to improve patient flow, patient experience, and decrease health system costs. A review of the clinical effectiveness and safety, cost-effectiveness as well as evidence-based guidelines could help clarify its role across different patient populations and care settings. The objectives of the review are to summarize the evidence regarding clinical effectiveness and cost-effectiveness of different delivery models of OPAT and to report on the recommendations found in evidence-based guidelines.
Details
Project Status: Ongoing
Anticipated Publish Date: 2027
English language abstract: An English language summary is available
Publication Type: Rapid Review
Country: Canada
MeSH Terms
  • Anti-Bacterial Agents
  • Ambulatory Care
  • Outpatients
  • Infusions, Parenteral
  • Anti-Infective Agents
Contact
Organisation Name: Canada’s Drug Agency (CDA-AMC)
Contact Address: 865 Carling Ave., Suite 600 Ottawa, ON Canada K1S 5S8
Contact Name: Shannon Nordstrom
Contact Email: shannon.nordstrom@cda-amc.ca
Copyright: 2025 Canadian Agency for Drugs and Technologies in Health
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