[Viral decontamination for lung transplants from HCV-seropositive donors using biophotonics]
D’ambrosio F, Gutiérrez-Ibarluzea I, Galnares-Cordero L
Record ID 32018015123
Spanish
Original Title:
Descontaminación vírica para trasplante de pulmones de donantes seropositivos para el VHC utilizando biofotónica
Authors' objectives:
To explore and analyse the literature related to the innovative field of viral decontamination of lungs for transplantation using biophotonics.
Authors' results and conclusions:
The studies retrieved focused primarily on evaluating the clinical effectiveness of biophotonic therapy with UV-C. Applying the inclusion and exclusion criteria, the final selection process led to the inclusion of three articles highlighting the potential of UV-C biophotonic therapy in the context of lung transplantation from HCV-positive donors to HCV-negative recipients.
Conclusions
Despite the findings gathered indicating the potentially significant impact of biophotonics in the prevention of virus transmission and HCV inactivation in the setting of LT, emphasis is placed on the need for additional research. This is because these findings are supported by a very limited number of studies, and among other limitations, these studies reported have had follow-up periods that were too short to assess long-term effects.
Authors' methods:
A scoping review of the literature was performed to identify studies providing evidence on the impact of using biophotonic technologies, specifically ultraviolet C (UV-C), in the viral decontamination of organs (lungs from donors with HCV infection) for transplantation. In July 2023, a search was conducted using specific search strings adapted to each database and built from the following keywords and synonyms: organ transplantation, biophotonics/light-based therapy, and hepatitis C.
Details
Project Status:
Completed
Year Published:
2024
URL for published report:
https://www.euskadi.eus/contenidos/informacion/2024_osteba_publicacion/eu_def/adjuntos/E-24-08-descontaminacion-virica.pdf
English language abstract:
An English language summary is available
Publication Type:
Rapid Review
Country:
Spain
MeSH Terms
- Tissue Donors
- Lung Transplantation
- Hepatitis C
- Light
- Decontamination
- Phototherapy
- Ultraviolet Rays
Keywords
- Biophotonics
- Light-based therapy
Contact
Organisation Name:
Basque Office for Health Technology Assessment
Contact Address:
C/ Donostia – San Sebastián, 1 (Edificio Lakua II, 4ª planta) 01010 Vitoria - Gasteiz
Contact Name:
Lorea Galnares-Cordero
Contact Email:
lgalnares@bioef.eus
Copyright:
<p>Osteba (Basque Office for Health Technology Assessment) Health Department of the Basque Government</p>
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.