Impact of radiation wait times on risk of local recurrence of breast cancer: early stage cancer with no chemotherapy
Benk V, Fisher A, Glazer D, Paszat L
Record ID 32004000338
English, French
Authors' objectives:
The aim of this review was to assess the relationship between the risk of local recurrence (LR) of breast cancer and the waiting times for radiotherapy (RT) after breast cancer surgery (BCS) among women with early stage breast cancer who are not receiving chemotherapy.
Authors' results and conclusions:
Among 194 potentially relevant reports, there were six retrospective, observational studies that examined the risk of LR of breast cancer among women who had undergone BCS followed by RT without chemotherapy. Waiting times in these studies varied from seven weeks, eight weeks (two studies), 12 weeks (two studies) and up to 20 weeks. Follow-up time varied from a mean of five years to a median of 8.4 years. The results were consistent between studies and revealed that there were no differences in the rate of LR of breast cancer among women who had to wait longer for RT after surgery compared to those who received earlier therapy. The impact of RT wait times on survival was not evaluated.
Authors' recommendations:
There was no difference in the LR rate of breast cancer among women who had earlier RT (less than eight weeks after BCS) and among those who had RT up to 12 weeks after BCS. As there were too few women waiting longer than 12 weeks, we could not evaluate the risk for this group.
Authors' methods:
Systematic review
Details
Project Status:
Completed
URL for project:
https://www.ccohta.ca/
Year Published:
2004
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
Canada
MeSH Terms
- Radiotherapy
- Time Factors
- Breast Neoplasms
Contact
Organisation Name:
Canadian Coordinating Office for Health Technology Assessment
Contact Address:
600-865 Carling Avenue, Ottawa, ON K1S 5S8 Canada. Tel: +1 613 226 2553, Fax: +1 613 226 5392;
Contact Name:
requests@cadth.ca
Contact Email:
requests@cadth.ca
Copyright:
Canadian Coordinating Office for Health Technology Assessment (CCOHTA)
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