[Clinical benefit of photon-counting computed tomorgraphy - a systematic review and assessment of medical, economical, ethical and organisational aspects]

HTA South
Record ID 32018014997
English
Original Title: Klinisk nytta med fotonräknande datortomografi - En systematisk översikt och utvärdering av medicinska, hälsoekonomiska, etiska och organisatoriska aspekter
Authors' objectives: To assess whether the use of photon-counting computed tomography (PCCT) compared with conventional CT and other imaging modalities has any impact on clinical benefit.
Authors' results and conclusions: Evidence regarding clinical benefit of photon-counting CT (PCCT) is limited and does not confirm a clear advantage. PCCT may improve diagnostic accuracy for coronary artery stenosis and influence downstream management, a possible benefit. It may increase detection rates of pancreatic cysts, which is difficult to define as a benefit or a risk. It may also improve classification of breast cancer tumors compared with conventional imaging, a possible benefit. For all other conditions, evidence is lacking regarding its effect on diagnostic reasoning and treatment decisions. Ethical concerns include inequity, poor cost-effectiveness, and resource allocation challenges, underscoring the need for robust research before widespread adoption.
Details
Project Status: Completed
Year Published: 2026
URL for published report: https://vardgivare.skane.se/kompetens-utveckling/sakkunniggrupper/hta-syd/
English language abstract: An English language summary is available
Publication Type: Full HTA
Country: Sweden
MeSH Terms
  • Tomography, X-Ray Computed
  • Image Processing, Computer-Assisted
  • Photons
  • Coronary Stenosis
  • Pancreatic Cyst
  • Cost-Effectiveness Analysis
  • Diagnostic Imaging
Keywords
  • Photon-counting CT
  • Photon-counting computed tomography
  • PCCT
  • Photon-counting detector computed tomography
  • radiology
  • X-ray radiation
Contact
Organisation Name: HTA South
Contact Address: Skåne University Hospital, Lund
Contact Name: hta.syd@skane.se
Contact Email: hta.syd@skane.se
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.