Leadless cardiac pacemakers

Semlitsch T, Krenn C, Berger N

Record ID 32018014480

English

Authors' objectives: Leadless cardiac pacemakers (L-PM) are miniaturised, fully implantable devices designed to avoid complications of conventional pacemakers.

Authors' results and conclusions: For single-chamber L-PMs for right ventricular pacing (VR), one randomised controlled trial (RCT) and seven cohort studies indicate an added benefit. However, this evidence is limited to less robust cohort studies. For AV-synchronous L-PMs (atrioventricular-synchronous L-PMs), evidence suggests potentially higher safety but possibly lower effectiveness. The evidence for dual-chamber leadless pacemakers and atrial L-PMs is currently insufficient due to a lack of comparative studies.

Authors' recommendations: Re-evaluation is recommended for 2028, as new RCT results are expected by the end of 2027.

Details

Project Status: Completed

URL for project: https://aihta.at/page/bewertung-medizinischer-einzelleistungen-mel-berichte/en

Year Published: 2025

URL for published report: https://eprints.aihta.at/1568/1/DSD_97_Update2025.pdf

URL for additional information: https://eprints.aihta.at/1568/

English language abstract: An English language summary is available

Publication Type: Full HTA

Country: Austria

MeSH Terms

Pacemaker, Artificial
Wireless Technology
Cardiac Pacing, Artificial
Atrial Fibrillation
Arrhythmias, Cardiac
Ventricular Dysfunction

Keywords

leadless
cardiac arrhythmias
heart rhythm disorders
implantation
Pacemakers

Contact

Organisation Name: Austrian Institute for Health Technology Assessment

Contact Address: Josefstaedter Strasse 39, A-1080 Vienna, Austria

Contact Name: office@aihta.at

Contact Email: office@aihta.at

This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.