[Paclitaxel-coated balloon dilatation in recurrent bulbar urethral strictures]
Rodriguez Scarso A, Ciapponi A, Alfie V, Merlotti L, Latorraca M, Garcia Marti S, Bardach A, Pichon Riviere A, Alcaraz A, Augustovski F
Record ID 32018013366
Spanish
Original Title:
Balón de dilatación con paclitaxel en pacientes con estenosis uretral bulbar recurrente versus dilatación simple o uretrotomía interna visual directa (DVIU)
Authors' recommendations:
Moderate-quality evidence shows that paclitaxel-coated balloon dilatation, when compared with endoscopic treatments (simple urethral dilatation/direct visual internal urethrotomy), in patients with recurrent bulbar urethral strictures, would produce a significant net benefit. This technology could result in a fast and sustained improvement in urinary symptoms, voiding function, quality of life parameters, and would reduce stricture recurrences. This was demonstrated by sustained reductions of more than 50% in the International Prostate Symptom Score two years after treatment, increased urinary flow rate, decreased post-void residual urine volume, and patient-reported outcomes. No evidence comparing paclitaxel-eluting balloon dilatation with urethroplasty has been found for recurrent bulbar urethral strictures.
The clinical practice guidelines consulted recommend the use of paclitaxel-coated balloon dilatation for recurrent bulbar ureth eligible for urethroplasty
The United Kingdom National Health Service (NHS) was the only health funder identified that included urethral drug-coated balloon (Optilume®) within its coverage, as part of the specialized services devices program.
No economic studies are available in Argentina or in the region for this technology and its cost-effectiveness could not be determined in Argentina either.
Details
Project Status:
Completed
Year Published:
2024
URL for published report:
https://ets.iecs.org.ar/publication/2202
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
Argentina
MeSH Terms
- Urethral Stricture
- Urologic Surgical Procedures, Male
- Paclitaxel
- Dilatation
Contact
Organisation Name:
Institute for Clinical Effectiveness and Health Policy
Contact Address:
Dr. Emilio Ravignani 2024, Buenos Aires - Argentina, C1414 CABA
Contact Name:
info@iecs.org.ar
Contact Email:
info@iecs.org.ar
Copyright:
<p>Institute for Clinical Effectiveness and Health Policy (IECS)</p>
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.