Causal association between IBS and COVID-19

WorkSafeBC Evidence-Based Practice Group, Martin CW
Record ID 32018013213
English
Authors' objectives: The Evidence-Based Practice Group (EBPG) was asked to investigate whether there is any evidence on the (causal) association between development of irritable bowel syndrome (IBS) post Covid-19 infection.
Authors' results and conclusions: Forty-eight published studies were identified. Upon examination on the titles and abstracts of these studies, 25 studies were thought to be relevant and were retrieved in full for further appraisal. Five published studies were identified from manual searches. As such, 30 studies were retrieved in full for further appraisal in this systematic review. Of these 30 studies, 21 did not provide relevant data/traced for the relevant primary studies/duplicitous publication of the same data/not relevant to the objective of this systematic review. Of the remaining nine studies, there is some low level, low-quality evidence (level of evidence 4) on the association of post Covid-19 infection and the development of IBS. Although some of these primary studies may show evidence on temporality, other criteria to provide causal association, such as on the size of the association and consistency of the association, may not yet be fulfilled with the available data. It should also be noted that the low-quality status of the primary studies included in this systematic review may not be able to exclude bias, chance, and confounding, and may affect the reported outcome of interest.
Authors' methods: A comprehensive and systematic literature search was conducted on January 26, 2024. The search was done on commercial and non-commercial medical literature databases. A combination of keywords was employed on this search. No limitation, such as on the language or date of publication, was implemented in this search. A manual search was also done on the references of the articles that were retrieved in full.
Details
Project Status: Completed
URL for project: https://www.worksafebc.com/en/about-us/research-services/evidence-based-medicine-and-systematic-reviews
Year Published: 2024
URL for published report: https://www.worksafebc.com/en/resources/health-care-providers/guides/causal-association-between-ibs-and-covid-19?lang=en&origin=s&returnurl=https%3A%2F%2Fwww.worksafebc.com%2Fen%2Fforms-resources%23sort%3DDate%26q%3DCausal%2520Association%2520Between%2520IBS%2520and%2520Covid-19%26f%3Alanguage-facet%3D%5BEnglish%5D%26tags%3DGuide%7C2d7eb4b30f6a4a319e0d40565c9abbab%2CHealth%2520Care%2520Provider%7C13468b0b3f074f6bade3f57ac3cdfb8e%2CSystematic%2520Review%7Cf78c29d570c14ec3b5a394385905df70&highlight=Causal%20Association%20Between%20IBS%20and%20Covid-19
English language abstract: An English language summary is available
Publication Type: Mini HTA
Country: Canada
MeSH Terms
  • COVID-19
  • Post-Acute COVID-19 Syndrome
  • SARS-CoV-2
  • Irritable Bowel Syndrome
Keywords
  • Post Acute COVID 19 Syndrome
  • Long Haul COVID
  • SARSCOV-2
  • Post Acute Sequelae of COVID 19
  • irritable bowel syndrome
Contact
Organisation Name: WorkSafeBC
Contact Address: 6591 Westminster Highway, Richmond, BC, V7C 1C6 Canada. Tel: 604-231-8417; Fax: 604-279-7698
Contact Name: ebpg@worksafebc.com
Contact Email: ebpg@worksafebc.com
Copyright: WorkSafe BC
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.