Thermoablation for benign thyroid nodules

Nicolopoulos K, Vreugdenburg T, Riegelnegg M, Hollyoak R
Record ID 32018013185
English
Authors' objectives: Thyroid nodules are typically benign and asymptomatic. However, occasionally nodules can cause compression of surrounding structures and changes in thyroid function. In such cases treatment is necessary. Thermoablation, a minimally invasive procedure, is one treatment option. Various forms of thermoablation typically use high temperatures to dissolve tissue and reduce nodule size. We investigated the safety and efficacy of thermoablation compared to conventional methods such as surgery or radioiodine therapy (ingestion of a radioactive capsule).
Authors' results and conclusions: The systematic review included four randomised controlled trials (n=648) and five non-randomised studies of interventions (propensity-score matching, n=1,605). The evidence suggests that fewer adverse events occur after thermoablation compared to surgery. However, the current evidence is insufficient to prove that thermoablation is more effective than conventional methods. Overall, the certainty of evidence concerning efficacy and safety was rated very low.
Authors' recommendations: Ongoing studies should be awaited, as they may provide significant evidence.
Details
Project Status: Completed
URL for project: https://aihta.at/page/bewertung-medizinischer-einzelleistungen-mel-2024/en
Year Published: 2024
URL for published report: https://eprints.aihta.at/1527/1/DSD_141.pdf
URL for additional information: https://eprints.aihta.at/1527/
English language abstract: An English language summary is available
Publication Type: Full HTA
Country: Austria
MeSH Terms
  • Ablation Techniques
  • Hyperthermia, Induced
  • Hypothermia, Induced
  • Radiofrequency Ablation
  • High-Intensity Focused Ultrasound Ablation
  • Thyroid Nodule
Keywords
  • Thermoablation
  • thyroid nodules
  • benign
  • radioiodine therapy
  • thyroidectomy
Contact
Organisation Name: Austrian Institute for Health Technology Assessment
Contact Address: Garnisongasse 7/20, A-1090 Vienna, Austria
Contact Name: office@aihta.at
Contact Email: office@aihta.at
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.