Molecular diagnosis for hereditary cancer predisposing syndromes: genetic testing and clinical impact
Ho C, Banerjee S, Mensinkai S
Record ID 32004000009
English, French
Authors' objectives:
To assess the evidence regarding the availability, cost, and analytical and clinical validity of genetic tests for screening and diagnosis of hereditary cancer predisposing syndromes.
To document the impact of genetic testing (GT) on the clinical management of patients with specific hereditary cancer predisposing syndromes.
Authors' recommendations:
Although new molecular techniques are being developed rapidly, the implementation of GT for many disorders into standard clinical management has not been justified. High cost, variable analytical and clinical validity, limited availability, and legal/social/ethical issues affect integration of GT into the health care system.
Authors' methods:
Systematic review
Details
Project Status:
Completed
URL for project:
https://www.ccohta.ca/
Year Published:
2003
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
Canada
MeSH Terms
- Costs and Cost Analysis
- Genetic Predisposition to Disease
- Neoplasms
- Neoplastic Syndromes, Hereditary
Contact
Organisation Name:
Canadian Coordinating Office for Health Technology Assessment
Contact Address:
600-865 Carling Avenue, Ottawa, ON K1S 5S8 Canada. Tel: +1 613 226 2553, Fax: +1 613 226 5392;
Contact Name:
requests@cadth.ca
Contact Email:
requests@cadth.ca
Copyright:
Canadian Coordinating Office for Health Technology Assessment (CCOHTA)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.