Repetitive transcranial magnetic stimulation in the management of chronic neuropathic pain
Gatzinsky K, Bergh C, Liljegren A, Silander H, Samuelsson J, Svanberg T, Samuelsson O
Record ID 32018011361
English
Authors' objectives:
Background
Neuropathic pain (NP) is defined as pain caused by a lesion or a disease that affects the somatosensory system. Clinical conditions with chronic NP often result in severe restrictions of activities of daily living and a reduced health related quality of life (HRQoL), with a concomitant risk for permanent disability. The available therapies, medical as well as physical, often fail to relieve the pain and other
symptoms. Invasive neuromodulation techniques can be considered when these therapies fail due to insufficient effect or intolerable side effects. Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive procedure for stimulation of the cerebral cortex. It offers an option for better treatment
of patients with neuropathic pain that is mainly of central origin. The response to rTMS has also been used to select patients who may be suitable for epidural motor cortex stimulation (MCS).
Objective
To evaluate whether rTMS can relieve pain better than placebo (sham treatment) in patients with chronic neuropathic pain, and whether the response to rTMS can predict the effect of MCS in these patients.
Authors' results and conclusions:
The present HTA analysis shows that multiple sessions of rTMS may result in a reduction of NP compared with sham stimulation. There is still a lack of knowledge about the effects of rTMS and MCS on HRQoL A single test session with rTMS seems to be a fairly good predictor of the response to epidural MCS. Repetitive transcranial magnetic stimulation should most likely primarily be used as a test method to adequately select patients suitable for epidural MCS.
Details
Project Status:
Completed
Year Published:
2017
URL for published report:
https://mellanarkiv-offentlig.vgregion.se/alfresco/s/archive/stream/public/v1/source/available/sofia/su4372-1728378332-329/native/2017_94%20HTA-rapport%20Repetitive%20transcranial%20magnetic%20stimulation.pdf
English language abstract:
An English language summary is available
Publication Type:
Full HTA
MeSH Terms
- Chronic Pain
- Neuralgia
- Transcranial Magnetic Stimulation
- Transcranial Direct Current Stimulation
- Pain Management
Keywords
- Neuropathic pain
- Repetitive Transcranial Magnetic Stimulation
- rTMS
Contact
Organisation Name:
The Regional Health Technology Assessment Centre
Contact Address:
The Regional Health Technology Assessment Centre, Region Vastra Gotaland, HTA-centrum, Roda Straket 8, Sahlgrenska Universitetssjukhuset, 413 45 GOTHENBORG, Sweden
Contact Name:
hta-centrum@vgregion.se
Contact Email:
hta-centrum@vgregion.se
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.