Effects of lung volume reduction with endobronchial valves in patients with severe chronic obstructive pulmonary disease. Updated report

Riise GC, Svanberg T, Samuelsson O
Record ID 32018011351
English
Authors' objectives: To assess whether lung volume reduction by EBVs improve survival, quality of life and pulmonary function in patients with severe COPD and severe pulmonary emphysema. To assess whether there are differences in outcome in patients treated with EBVs bilaterally or unilaterally. To assess whether there are differences in outcome in patients with homogeneous or heterogeneous emphysema.
Authors' results and conclusions: Based on moderate certainty of evidence, lung volume reduction in patients with advanced chronic obstructive pulmonary disease and emphysema by the insertion of one-way valves in affected lung segments probably leads to clinically relevant improvement in lung function, quality of life, and physical capacity up to 12 months after treatment. Short-term complications to the procedure are frequent and reliable data on mortality are still lacking. Further long-term studies are needed to address whether the effects are sustainable and to clarify the effects on long-term survival.
Details
Project Status: Completed
Year Published: 2018
URL for published report: https://mellanarkiv-offentlig.vgregion.se/alfresco/s/archive/stream/public/v1/source/available/sofia/su4372-1728378332-340/native/2018_103%20HTA-rapport%20tEffects_of_lung_volume_reduction.pdf
English language abstract: An English language summary is available
Publication Type: Full HTA
MeSH Terms
  • Pulmonary Disease, Chronic Obstructive
  • Bronchoscopy
  • Emphysema
  • Pneumonectomy
Keywords
  • Endobroncial valve
  • Lung volume reduction
Contact
Organisation Name: The Regional Health Technology Assessment Centre
Contact Address: The Regional Health Technology Assessment Centre, Region Vastra Gotaland, HTA-centrum, Roda Straket 8, Sahlgrenska Universitetssjukhuset, 413 45 GOTHENBORG, Sweden
Contact Name: hta-centrum@vgregion.se
Contact Email: hta-centrum@vgregion.se
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.