[Autologous adipose-derived stem cells for chronic wounds treatment : Full HTA report]

Harzallah N, Akid A, Grati H, Jebali MC, Jameleddine M
Record ID 32018011330
French
Original Title: Autogreffe de cellules souches issues du tissu adipeux dans le traitement des plaies chroniques
Authors' objectives: This HTA report examines the clinical, economic ethical, legal, social, and organizational implications of autologous adipose-derived stem cells (ASCs) as an innovative treatment approach for chronic wounds
Authors' results and conclusions: Preliminary ASC studies show promise, prompting the need for rigorous validation through well-designed clinical trials.
Authors' recommendations: Preliminary studies on ASC show promising results, underscoring the imperative of rigorous validation in meticulously designed clinical trials. This Health Technology Assessment (HTA) makes a strong case for further exploration through large-scale trials with extended follow-up. Highlighting the importance of respecting ethical considerations and rigorous legal standards, while offering foundational insights for future research in regenerative medicine in Tunisia
Authors' methods: The assessment of effectiveness, security and economic implications was based on a systematic literature review. Legal status of the technology in other settings was determined through a literature review and a survey through INAHTA. Ethical, legal, social, and organizational implications were assessed on the basis of experts opinion according to INEAS guidelines, providing valuable insights that complemented the literature review.
Details
Project Status: Completed
Year Published: 2023
URL for published report: https://portail.ineas.tn/Default/digital-viewer/c-1272
Requestor: Tunisian Association for Wounds and Cicatrisations /Tunisian Association for Stem Cell Research
URL for additional information: https://portail.ineas.tn/
English language abstract: An English language summary is available
Publication Type: Full HTA
Country: Tunisia
MeSH Terms
  • Wounds and Injuries
  • Adipose Tissue
  • Wound Healing
  • Stem Cells
Keywords
  • Chronic wounds
  • Autologous adipose-derived stem cells (ASCs)
  • Clinical
  • economic
  • ethical
  • legal
  • social
  • and organizational implications
  • Systematic literature review
Contact
Organisation Name: National Authority for Assessment and Accreditation in Healthcare (INEAS)
Contact Address: 30 Rue Ibn Charaf, Tunis 1002, Tunisia
Contact Name: Mouna Jameleddine
Contact Email: monajameleddine@gmail.com
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.