Pallidotomy for Parkinson's disease

Robert G
Record ID 31998008869
Authors' objectives:

The author explores whether pallidotomy is effective in reducing the symptoms of Parkinson's disease.

Authors' results and conclusions: One study of 126 patients found, based on patients' subjective reports, excellent results (total alleviation or remarkable improvement of symptoms) in nearly half (61 patients); good results in 45; and fair results in 18, with 2 unchanged. At least one other study found similar proportions, though one found no observable change.
Authors' recommendations: The author considers that the case for pallidotomy is not proven, although the treatment holds potential. Poor outcomes are not unusual at new centres and some published success rates have been overestimated, complication rates underestimated and statistical analysis oversimplified. Randomised controlled trials should be undertaken to evaluate the technique.
Authors' methods: Overview.
Project Status: Completed
URL for project:
Year Published: 1996
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: England
MeSH Terms
  • Costs and Cost Analysis
  • Globus Pallidus
  • Parkinson Disease
Organisation Name: Wessex Institute for Health Research and Development
Contact Address: Pauline King. Wessex Institute for Health Research and Development, Boldrewood Medical School, Bassett Crescent East, Highfield, Southampton. SO16 7PX Tel. +44 1703 595661 Fax +44 1703 595662
Copyright: Wessex Institute for Health Research and Development (WIHRD)
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