Antibiotic therapy for acute appendicitis: Ampicillin, metronidazole plus gentamycin versus cephalosporin
Muggli E
Record ID 32003000705
English
Authors' objectives:
This aim of this report was to assess which antibiotic regimen is more appropriate for acute appendicitis: Ampicillin, metronidazole plus gentamycin or cephalosporin (+/- metronidazole).
Authors' recommendations:
- One randomised trial was reviewed that met inclusion and exclusion criteria.
- The trial combined children with appendicitis from the age of 12 years with adults to the age of 48 years.
- This study found ceftriaxone, a cephalosporin, to be equally effective as a triple regimen of ampicillin, metronidazole plus gentamycin in the prophylaxis for postoperative sepsis.
Authors' methods:
Review
Details
Project Status:
Completed
URL for project:
http://www.med.monash.edu.au/healthservices/cce/evidence/
Year Published:
2002
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
Australia
MeSH Terms
- Anti-Bacterial Agents
- Appendicitis
Contact
Organisation Name:
Centre for Clinical Effectiveness
Contact Address:
Monash Institute of Health Services Research, Block E, Monash Medical Centre, Locked Bag 29, Clayton, Victoria 3168, Australia. Tel: +61 3 9594 7505; Fax: +61 3 9594 7552.
Contact Name:
cce@med.monash.edu.au.
Contact Email:
cce@med.monash.edu.au.
Copyright:
Centre for Clinical Effectiveness (CCE)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.