What is the sensitivity and specificity of ultrasonography in the diagnosis of calf vein thrombosis?
Record ID 32003000691
This aim of this report was to assess the sensitivity and specificity of ultrasonography in the diagnosis of calf vein thrombosis.
Authors' recomendations: - Seven studies that met inclusion and exclusion criteria were retrieved. They were systematic reviews (2), meta-analyses (2), prospective studies (2), and one retrospective review. Of these seven studies, four evaluated the accuracy of ultrasonography in detecting calf thrombosis and compared it to venography. - The studies showed variable diagnostic characteristics for ultrasonography. - Sensitivity: Ranging from 13% to 100%. - Specificity: Ranging from 79% to 98%. - Positive predictive value: Ranging from 60% to 95%. - Negative predictive value: Ranging from 55% to 100%. - There were significant methodological problems associated with the retrieved studies that included: - Variations in the study population or patient spectrum (symptomatic, asymptomatic, outpatients, inpatients). - Inadequate descriptions of patient spectrum, setting, and characteristics of study subjects. - Retrieval and publication biases: The keyword calf was not included in the search terms in the systematic reviews and meta-analyses. The literature search for the reviews was also limited to Medline database and there was hardly any attempt to identify unpublished articles. - Differences in the study design or review method across the retrieved articles.
Authors' methods: Review
Project Status: Completed
URL for project: http://www.med.monash.edu.au/healthservices/cce/evidence/
Year Published: 2001
English language abstract: An English language summary is available
Publication Type: Not Assigned
- Venous Thrombosis
Organisation Name: Centre for Clinical Effectiveness
Contact Address: Monash Institute of Health Services Research, Block E, Monash Medical Centre, Locked Bag 29, Clayton, Victoria 3168, Australia. Tel: +61 3 9594 7505; Fax: +61 3 9594 7552.
Contact Name: firstname.lastname@example.org.
Contact Email: email@example.com.
Copyright: Centre for Clinical Effectiveness (CCE)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.