What is the optimal dose of intravenous corticosteroid for initial management of acute exacerbations of asthma and COPD?
Record ID 32003000673
This aim of this report was to assess the optimal dose of intravenous corticosteroid for initial management of acute exacerbations of asthma and COPD.
Authors' recommendations: - One systematic review was identified that met the inclusion and exclusion criteria - Varying doses of corticosteroids used in the treatment of admitted patients with acute asthma appear to result in similar outcomes when pulmonary function data are examined. - Higher doses of corticosteroids do not appear to have an obvious therapeutic advantage for severe asthma patients - The results may not be generalisable to COPD patients, mild asthmatics, or patients with ventilatory support. - We are unable to determine the effect of differing doses of corticosteroids on time to discharge, adverse events or quality of life. - We are unable to reach conclusions regarding the dosing effect for intravenous and oral corticosteroids individually.
Authors' methods: Review
Project Status: Completed
URL for project: http://www.med.monash.edu.au/healthservices/cce/evidence/
Year Published: 2000
English language abstract: An English language summary is available
Publication Type: Not Assigned
- Adrenal Cortex Hormones
- Pulmonary Disease, Chronic Obstructive
Organisation Name: Centre for Clinical Effectiveness
Contact Address: Monash Institute of Health Services Research, Block E, Monash Medical Centre, Locked Bag 29, Clayton, Victoria 3168, Australia. Tel: +61 3 9594 7505; Fax: +61 3 9594 7552.
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Copyright: Centre for Clinical Effectiveness (CCE)
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