Fetal fibronectin for the prediction of preterm labor

Institute for Clinical Systems Improvement
Record ID 32003000548
English
Authors' objectives:

This review aims to assess the available evidence on the effectiveness of fetal fibronectin for the prediction of preterm labor.

Authors' recommendations: With regard to the use of fetal fibronectin (fFN) for the prediction of preterm labor, the ICSI Technology Assessment Committee finds the following: Symptomatic high-risk patients with a negative test result are highly unlikely to experience PTD within the next 7 days. The benefit of testing for fFN is a result of the high negative predictive value of the test. (Conclusion Grade I) Testing for fFN is a safe procedure; the risks and limitations of the test are related to the false negative rate and the false positive rate. The clinical importance of a positive test remains unclear. The fFN test is not recommended as a screening test for asymptomatic patients, regardless of risk status.
Authors' methods: Review
Details
Project Status: Completed
Year Published: 2000
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: United States
MeSH Terms
  • Fibronectins
  • Obstetric Labor, Premature
Contact
Organisation Name: Institute for Clinical Systems Improvement
Contact Address: 8009 34th Avenue South, Suite 1200, Bloomington, MN, USA. Tel: +1 952 814 7060; Fax: +1 952 858 9675
Contact Name: icsi.info@icsi.org
Contact Email: icsi.info@icsi.org
Copyright: Institute for Clinical Systems Improvement (ICSI)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.