Best-case series for the use of immuno-augmentation therapy and naltrexone for the treatment of cancer

Coulter I, Hardy M, Shekelle P
Record ID 32003000531
English
Authors' objectives:

The primary objective of this project was to create a best-case series for two complementary and alternative medicine (CAM) therapies for treating cancer patients: immuno-augmentation therapy (IAT) and low-dose naltrexone.

Authors' results and conclusions: For both therapies, it was extremely difficult to meet the full documentation requirements of the NCI best-case series criteria. For IAT, nine cases were found that we consider the most complete or appropriate in terms of the NCI criteria for a best-case series. For naltrexone treatments, only three cases best met the NCI criteria. These cases represent the best that we were able to assemble using the currently accepted best-case method of the NCI.
Authors' recommendations: Assembling documentary evidence for a best-case series through retrospective case analysis for CAM therapy will seldom meet the full NCI criteria. An alternative approach might be to establish a prospective case series.
Authors' methods: Case study
Details
Project Status: Completed
Year Published: 2003
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: United States
MeSH Terms
  • Complementary Therapies
  • Immunotherapy
  • Naltrexone
  • Neoplasms
Contact
Organisation Name: Agency for Healthcare Research and Quality
Contact Address: Center for Outcomes and Evidence Technology Assessment Program, 540 Gaither Road, Rockville, MD 20850, USA. Tel: +1 301 427 1610; Fax: +1 301 427 1639;
Contact Name: martin.erlichman@ahrq.hhs.gov
Contact Email: martin.erlichman@ahrq.hhs.gov
Copyright: Agency for Healthcare Research and Quality (AHRQ)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.