Use of diagnostic immunohistochemistry and electron microscopy tests in Belgium (Study 2021-01)

Record ID 32018005495
Authors' objectives: The number of immunohistochemistry (IHC) and electron microscopy tests (EM) carried out in Belgium has increased over the past few years. There is a lack of information on the main indications of such tests and on the basis on which decisions are made. With this in mind, the NIHDI approached KCE with a request to study this field. Our study aims to answer two research questions: 1. How are Immunohistochemistry (IHC) and Electron Microscopy (EM) diagnostic tests currently used in Belgium? A survey among Belgian anatomical pathology laboratories and an analysis of administrative data will be carried out to identify the most frequent clinical indications for these techniques and explore the basis on which decisions are made in this field. 2. What is the clinical value of these types of diagnostic tests? A comprehensive review of the clinical evidence (limited to systematic reviews and guidelines) will be performed for the most common indications. We hope this research will enable us to draw informed conclusions about the use of these techniques in the Belgian healthcare system, increasing transparency and understanding in the field.
Project Status: Ongoing
Anticipated Publish Date: 2024
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Belgium
MeSH Terms
  • Immunohistochemistry
  • Microscopy, Electron
  • Diagnostic Tests, Routine
  • Medical Overuse
  • Immunohistochemistry (IHC)
  • Electron Microscopy (EM)
  • Diagnostic tests
Organisation Name: Belgian Health Care Knowledge Centre
Contact Address: Administrative Centre Botanique, Doorbuilding (10th floor), Boulevard du Jardin Botanique 55, B-1000 Brussels, Belgium tel: +32 2 287 33 88 fax: +32 2 287 33 85
Contact Name:
Contact Email:
Copyright: <p>Belgian Health Care Knowledge Centre (KCE)</p>
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