The use of endothelial cell counting in the preoperative evaluation of cataract surgery (Study 2023-12)

Record ID 32018005493
Authors' objectives: The corneal endothelium is a single-cell layer that lines the posterior surface of the cornea. It is involved in keeping the cornea clear. Any injury to this layer results in a decrease of the number of cells, and cataract surgery too inevitably induces a ‑ limited ‑ decrease in the number of corneal endothelial cells. Although advances in cataract surgery have made it possible to limit endothelial cell injury, there are several conditions in which endothelial cell loss can negatively impact the post-operative visual outcome due to the loss of corneal transparency. Corneal endothelial cell counting through specular microscopy is a diagnostic procedure which allows the ophthalmologist to examine the structure of the cornea to identify any diseases or follow up postoperative processes. It can for instance be performed before deciding to proceed with a cataract operation. The number of endothelial cell countings before a cataract surgery has considerably increased over the past few years in Belgium. This study consists of a systematic review of the literature on the clinical and cost-effectiveness impacts of corneal endothelial cell counting before cataract surgery. A description of the organisational and financial aspects of the use of endothelial cell counting in Belgium – and in a selection of neighbouring countries – will be provided. Based on the findings, the recommendations of this study should help policymakers to optimise the use and reimbursement of endothelial cell counting in the setting of cataract surgery.
Project Status: Ongoing
Anticipated Publish Date: 2024
English language abstract: An English language summary is available
Publication Type: Rapid Review
Country: Belgium
MeSH Terms
  • Cataract
  • Cataract Extraction
  • Corneal Endothelial Cell Loss
  • Cell Count
  • Endothelium, Corneal
  • preoperative evaluation
  • cataract surgery
  • corneal endothelium
  • cell counting
  • microscopy
  • diagnostic procedure
Organisation Name: Belgian Health Care Knowledge Centre
Contact Address: Administrative Centre Botanique, Doorbuilding (10th floor), Boulevard du Jardin Botanique 55, B-1000 Brussels, Belgium tel: +32 2 287 33 88 fax: +32 2 287 33 85
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Copyright: <p>Belgian Health Care Knowledge Centre (KCE)</p>
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