Creatine supplementation for treating concussions

WorkSafeBC Evidence-Based Practice Group, Martin CW
Record ID 32018005432
English
Authors' objectives: To determine whether there is any evidence for the efficacy and/or effectiveness of creatine in treating patients with concussions.
Authors' results and conclusions: Two-hundred and nine published studies were identified in our search. Upon examination on the titles and abstracts of these two-hundred and nine studies, fifteen studies were thought to be relevant and were retrieved in full for further appraisal. At present, there is no data to support the efficacy and/or effectiveness of creatine supplement to treat mild traumatic brain injury/concussive patients. At present, there are two randomized controlled trial protocols investigating the efficacy and/or effectiveness of creatine supplement in treating patients with persistent postconcussive symptoms. However, these studies have not recruited any participants.
Authors' methods: A comprehensive and systematic literature search was conducted on May 30, 2023. The search was done on commercial medical literature databases with no limitation, such as on the language and year of publication, was implemented in this search. With regard to expert and/or systematic review articles that were identified in our literature search, instead of appraising and summarizing these articles, we decided to trace and retrieve the relevant primary studies included in these review articles. These manually retrieved primary studies were then appraised and summarized when appropriate. We also manually searched the references of all the articles that we retrieved in full for further potentially relevant primary studies.
Details
Project Status: Completed
Year Published: 2023
English language abstract: An English language summary is available
Publication Type: Mini HTA
Country: Canada
MeSH Terms
  • Brain Concussion
  • Brain Injuries, Traumatic
  • Creatine
  • Post-Concussion Syndrome
  • Creatine Kinase
Keywords
  • Concussion
  • mild traumatic brain injury
  • creatine
Contact
Organisation Name: WorkSafeBC
Contact Address: 6591 Westminster Highway, Richmond, BC, V7C 1C6 Canada. Tel: 604-231-8417; Fax: 604-279-7698
Contact Name: ebpg@worksafebc.com
Contact Email: ebpg@worksafebc.com
Copyright: WorkSafe BC
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.