Human skin allograft for burns
Nur Farhana M, Roza S, Izzuna MMG
Record ID 32018005410
English
Authors' objectives:
To evaluate the effectiveness, safety, organisational and economic implications of the use of human skin allograft in burns.
Authors' results and conclusions:
Based on the review, highly limited evidence found that the use of human skin allograft may be effective in terms of patient survival and inpatient mortality for patients with major burns. Its use was considered safe through the pathway of the skin bank. Very limited evidence showed its use for burn patients was associated with higher cost compared to other skin substitutes but can be cost-effective depending on the willingness-to-pay thresholds.
Authors' recommendations:
Human skin allograft can be used in the management of patients with major burns. However, to ensure safety, it should be acquired from trusted sources. Although the use of human skin allograft in burns was associated with higher costs, it may be considered in selected patients.
Authors' methods:
A comprehensive search was conducted on the following databases without any restriction on publication language and publication status. The Ovid interface: Ovid MEDLINE(R) and Epub Ahead of Print, In-Process, In-Data-Review & Other Non-Indexed Citations and Daily 1946 to Jan 9, 2023. Searches were also run in PubMed and INAHTA databases. Google was used to search for additional web-based materials and information. Additional articles were identified by reviewing the references of retrieved articles. The last search was conducted on 9th January 2023.
Authors' identified further research:
-
Details
Project Status:
Completed
Year Published:
2023
URL for published report:
https://www.moh.gov.my/index.php/database_stores/store_view_page/30/401
Requestor:
Decision-making committee
English language abstract:
An English language summary is available
Publication Type:
Mini HTA
Country:
Malaysia
MeSH Terms
- Burns
- Allografts
- Skin Transplantation
- Wound Healing
Contact
Organisation Name:
Malaysian Health Technology Assessment
Contact Address:
Malaysian Health Technology Assessment Section, Ministry of Health Malaysia, Federal Government Administrative Centre, Level 4, Block E1, Parcel E, 62590 Putrajaya Malaysia Tel: +603 8883 1229
Contact Name:
htamalaysia@moh.gov.my
Contact Email:
htamalaysia@moh.gov.my
Copyright:
Malaysian Health Technology Assessment Section (MaHTAS)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.