Authors' objectives: What is the clinical effectiveness of a midline catheter versus and an extended dwell catheter for delivering IV peripherally compatible antibiotics in adults? What are the evidence-based guidelines regarding midline and extended dwell catheters for delivering IV peripherally compatible antibiotics in adults?

Authors' results and conclusions: Midline catheters may be associated with longer uncomplicated indwelling time and a lower overall risk of catheter-related complications than extended dwell catheters. The rates of catheter-related complications were low across different peripheral catheter types. Midline catheters may have a lower proportion of catheter-related bloodstream infections, drug leakage from the exit site, and complete catheter occlusion, but a higher proportion of catheter-related thrombosis events compared with extended dwell catheters. The findings were derived from 1 retrospective cohort study with imbalanced baseline characteristics of patients, and the limitations of the study may have favoured midline catheters; future studies are needed to confirm our findings. We did not find any systematic reviews, health technology assessments, randomized controlled trials, or evidence-based guidelines that met our inclusion criteria.

Project Status: Completed

URL for project: https://www.cadth.ca/midline-and-extended-dwell-catheters-iv-antibiotics

Year Published: 2023

URL for published report: https://www.cadth.ca/midline-and-extended-dwell-catheters-iv-antibiotics

English language abstract: An English language summary is available

Publication Type: Rapid Review

Country: Canada

Organisation Name: Canadian Agency for Drugs and Technologies in Health

Contact Address: 600-865 Carling Avenue, Ottawa, ON K1S 5S8 Canada. Tel: +1 613 226 2553; Fax: +1 613 226 5392;

Contact Name: requests@cadth.ca

Contact Email: requests@cadth.ca

Copyright: <p>Canadian Agency for Drugs and Technologies in Health (CADTH)</p>