Systemic thrombolysis and endovascular therapy for large vessel occlusion acute ischemic stroke
Farrell K, Askin N
Record ID 32018005183
English
Authors' objectives:
The aim of the current report is to summarize the evidence regarding the comparative clinical effectiveness of systemic thrombolysis with alteplase combined with EVT versus EVT alone in patients with large vessel occlusion acute ischemic stroke.
Authors' results and conclusions:
Evidence was mixed, with higher-quality evidence suggesting that there were no differences between treatment with alteplase before endovascular therapy or endovascular therapy alone in patients with large vessel occlusion acute ischemic stroke for outcomes related to safety and efficacy, and lower-quality evidence indicating a difference between the groups for certain outcomes.
Details
Project Status:
Completed
URL for project:
https://www.cadth.ca/systemic-thrombolysis-and-endovascular-therapy-large-vessel-occlusion-acute-ischemic-stroke
Year Published:
2022
URL for published report:
https://www.cadth.ca/sites/default/files/pdf/htis/2022/RD0067-EVT-and-alteplase-for-LVO-AIS.pdf
English language abstract:
An English language summary is available
Publication Type:
Rapid Review
Country:
Canada
MeSH Terms
- Ischemic Stroke
- Stroke
- Thrombolytic Therapy
- Fibrinolytic Agents
- Endovascular Procedures
- Tissue Plasminogen Activator
- Thrombectomy
- Mechanical Thrombolysis
Contact
Organisation Name:
Canadian Agency for Drugs and Technologies in Health
Contact Address:
600-865 Carling Avenue, Ottawa, ON K1S 5S8 Canada. Tel: +1 613 226 2553; Fax: +1 613 226 5392;
Contact Name:
requests@cadth.ca
Contact Email:
requests@cadth.ca
Copyright:
<p>Canadian Agency for Drugs and Technologies in Health (CADTH)</p>
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.