Percutaneous mitral valve repair with a clip device in patients with mitral regurgitation. Update 2023

Semlitsch T, Loder C
Record ID 32018004887
Authors' objectives: Mitral valve regurgitation is the second most common valvular heart disease in adults and is a progressive disease associated with reduced life expectancy. The mitral clip procedure is a percutaneous intervention to reduce mitral regurgitation and is a potential alternative to medical or surgical treatment.
Authors' results and conclusions: A total of 1 RCT (n=279) of percutaneous mitral valve repair using the mitral clip compared with surgery or 3 RCTs (n=952) compared with medical therapy were identified. The evidence suggests that the mitral clip is less effective than surgery. The trials showed inconsistent results compared with medical therapy. Therefore, it is not possible to conclude whether percutaneous mitral valve repair with the mitral clip is more effective than optimal medical therapy alone.
Project Status: Completed
Year Published: 2023
URL for additional information:
English language abstract: An English language summary is available
Publication Type: Full HTA
Country: Austria
MeSH Terms
  • Mitral Valve
  • Percutaneous Coronary Intervention
  • Mitral Valve Insufficiency
  • Heart Valve Prosthesis Implantation
  • Mitral clip
  • Mitral valve regurgitation
Organisation Name: Austrian Institute for Health Technology Assessment
Contact Address: Garnisongasse 7/20, A-1090 Vienna, Austria
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