Optimal temperature for cardioplegia during coronary artery bypass grafting: a systematic review of published randomized controlled trials for myocardial protection
Flynn K
Record ID 32003000159
English
Authors' objectives:
This qualitative systematic review addresses the optimal temperature in cardiopulmonary bypass (CPB) and cardioplegia during cardiovascular surgery. Specific attention was given to defining the optimal method for myocardial protection during coronary artery bypass grafting (CABG).
Authors' results and conclusions:
Seventeen published randomized controlled trials (one yielding two separate publications) met inclusion criteria for this review. The searches also identified three published analyses of large databases relevant to cardioplegia temperature, two of which used data from randomized controlled trials. Results from these studies support the American College of Cardiology/American Heart Association (ACC/AHA) guidelines for CABG (1999).
Authors' recommendations:
The ACC/AHA guidelines for CABG (1999) states "no strong argument can currently be made for warm versus cold and crystalloid versus blood cardioplegia" in patients with normal left ventricular function.
Additional research is needed to determine the optimal temperature for cardiopulmonary bypass and cardioplegia during cardiovascular surgery. Specific attention should be given to defining the optimal method for myocardial protection during CABG.
Authors' methods:
Systematic review
Details
Project Status:
Completed
URL for project:
http://www4.va.gov/VATAP/docs/TemperatureCardioplegiaArteryBypassGrafting2003tm.pdf
Year Published:
2003
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
United States
MeSH Terms
- Body Temperature
- Cardiopulmonary Bypass
- Heart Arrest, Induced
- Temperature
Contact
Organisation Name:
VA Technology Assessment Program
Contact Address:
Liz Adams, VA Technology Assessment Program, Office of Patient Care Services (11T), VA Boston Healthcare System Room 4D-142, 150 South Huntington Avenue, Boston, MA 02130 USA Tel: +1 617 278 4469; Fax: +1 617 264 6587;
Contact Name:
elizabeth.adams@med.va.gov
Contact Email:
elizabeth.adams@med.va.gov
Copyright:
Technology Assessment Unit, Office of Patient Care Services, US Department of Veterans Affairs (VATAP)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.