Upper airway stimulation for moderate-to-severe sleep apnoea. Update 2022

Hofer V, Wild C
Record ID 32018002662
English
Authors' objectives: Obstructive sleep apnoea (OSA) is a sleep-related breathing disorder due to upper airway collapse. Current standard therapy is CPAP therapy, but its effectiveness is limited due to poor compliance. An alternative therapeutic approach is the electrical stimulation of the hypoglossal nerve (HGNS), using an implant to promote airway opening.
Authors' results and conclusions: The update search provided one comparative parallel-arm study for the evaluation of efficacy and one sham-controlled crossover RCT as well as two observational studies for the evaluation of safety. Compared to no therapy, improvements in efficacy endpoints were observed with HGNS after one year. Several serious adverse events were recorded in the observational studies, most of which were due to serious adverse device-related events. The available evidence does not allow valid conclusions to be drawn about the efficacy of HGNS compared to no therapy and whether HGNS is safe in the target population.
Authors' methods: For this second update on the assessment of the efficacy and safety of HGNS, an update search was conducted and an EUnetHTA report from 2020 was used as a basis.
Details
Project Status: Completed
URL for project: https://aihta.at/page/bewertung-medizinischer-einzelleistungen-mel-berichte/en
Year Published: 2022
URL for published report: https://eprints.aihta.at/1387/1/DSD_100_Update2022.pdf
URL for additional information: https://eprints.aihta.at/1387
English language abstract: An English language summary is available
Publication Type: Full HTA
Country: Austria
MeSH Terms
  • Sleep Apnea, Obstructive
  • Electric Stimulation
  • Hypoglossal Nerve
  • Electric Stimulation Therapy
  • Sleep Apnea Syndromes
Keywords
  • Obstructive sleep apnoea
  • hypoglossal nerve
  • electrical stimulation
Contact
Organisation Name: Austrian Institute for Health Technology Assessment
Contact Address: Garnisongasse 7/20, A-1090 Vienna, Austria
Contact Name: office@aihta.at
Contact Email: office@aihta.at
Copyright: HTA Austria - AIHTA GmbH
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.