[Teduglutide in short bowel syndrome]

Donato M, Ciapponi A, Alfie V, Rojas C, Klappenbach R, Bardach A, Augustovski F, Garcia Marti S, Alcaraz A, Pichon Riviere A
Record ID 32018002312
Original Title: Teduglutida en síndrome de intestino corto
Authors' recomendations: Low-quality evidence suggests that the use of teduglutide in parenteral nutrition-dependent patients with short bowel syndrome and subsequent intestinal failure over-one-year-old might significantly reduce parenteral support requirements at medium term. However, the use of teduglutide did not show improvement in the nutritional status of pediatric patients and showed a significantly higher rate of serious adverse events (most of them gastrointestinal) and treatment discontinuation versus the standard of care.
Project Status: Completed
Year Published: 2021
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Argentina
MeSH Terms
  • Short Bowel Syndrome
  • Gastrointestinal Agents
  • Parenteral Nutrition
  • Peptides
Organisation Name: Institute for Clinical Effectiveness and Health Policy
Contact Address: Dr. Emilio Ravignani 2024, Buenos Aires - Argentina, C1414 CABA
Contact Name: info@iecs.org.ar
Contact Email: info@iecs.org.ar
Copyright: Institute for Clinical Effectiveness and Health Policy (IECS)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.