MARS (R) liver support (Molecular Adsorbents Recirculating System)

Comite d'Evaluation et de Diffusion des Innovations Technologiques
Record ID 32002000818
Authors' objectives:

This report aims to assess the effectiveness of the MARS (R) liver support therapy purification technique.

Authors' recomendations: The CEDIT estimates that the technology has not been sufficiently evaluated in order for us to recommend its widespread use. The CEDIT recommends a clinical and economic evaluation of the use of the MARS liver support therapy in the AP-HP. Such a study would bring together the five departments of the AP-HP currently equipped, and would provide data on effectiveness and economic and organizational issues involved in the use of MARS. It would collect data on long-term patient follow-up and the most relevant indications for the therapy. The evaluation would be placed under a multi-disciplinary scientific committee including hepatologists, ICU staff, transplant specialists and nephrologists. The feasability study would aim at specifying technical conditions (compatibility of available dialysis equipment with MARS), and human resources required for its set-up and for follow-up of patients treated. An agreement between the departments of the AP-HP would have to be obtained on setting up the clinical and economic registry. The CEDIT strongly emphasizes that use of MARS from TERAKLIN in the AP-HP be strictly limited to the five centers already equipped so far.
Authors' methods: Systematic review
Project Status: Completed
URL for project:
Year Published: 2001
English language abstract: An English language summary is available
Publication Type: Not Assigned
MeSH Terms
  • Costs and Cost Analysis
  • Liver, Artificial
  • Liver Failure
Organisation Name: Cellule Innovation of the AP-HP
Copyright: Comite d'Evaluation et de Diffusion des Innovations Technologiques (CEDIT)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.