[Prostate rectum spacing in prostate radiation therapy]
Oubiña M, Alfie V, Ciapponi A, Pichon-Riviere A, Augustovski F, García Martí S, Alcaraz A, Bardach A.
Record ID 32018001549
Spanish
Original Title:
Espaciamiento prostático-rectal en radioterapia prostática
Authors' recommendations:
Moderate-quality evidence suggests that prostate-rectum spacing using polyethylene glycol, hyaluronic acid, collagen or biodegradable balloon is associated with a decrease in late rectal toxicity in patients receiving external radiation therapy or brachytherapy when compared with patients who did not use them, although no differences were found in terms of acute toxicity. A significant decrease in the radiation received in the rectum was observed in those patients treated with that technology when compared with those who did not use it. A greater number of patients presented significant clinical improvements in quality of life three years after spacer placement.
Very low-quality evidence does not allow to draw conclusions about the effectiveness or safety of prostate-rectum spacing with autologous fat. The only study surveyed assesses the feasibility of creating an adequate prostate-rectum space, similar to that of synthetic spacers, but the clinical results were not assessed.
The clinical practice guidelines mention the use of rectal spacers as a strategy to reduce the rectal toxicity produced during prostate radiation therapy. The use of rectal spacers is not considered in Argentina’s Mandatory Medical Plan and it is not reimbursable. The United Kingdom public health funders and some private United States health funders cover this procedure, but the public funders do not. None of the clinical practice guidelines or coverage policies surveyed mentions the use of autologous fat as a rectal spacer.
The cost-effectiveness of these procedures in Argentina is unknown. It is possible that not all technologies evaluated in this document are available in Argentina.
Details
Project Status:
Completed
Year Published:
2019
URL for published report:
https://www.iecs.org.ar/home-ets/
English language abstract:
An English language summary is available
Publication Type:
Not Assigned
Country:
Argentina
MeSH Terms
- Prostatic Neoplasms
- Radiation Injuries
- Hydrogels
- Rectum
- Hydrogel, Polyethylene Glycol Dimethacrylate
- Radiotherapy Dosage
Contact
Organisation Name:
Institute for Clinical Effectiveness and Health Policy
Contact Address:
Dr. Emilio Ravignani 2024, Buenos Aires - Argentina, C1414 CABA
Contact Name:
info@iecs.org.ar
Contact Email:
info@iecs.org.ar
Copyright:
Institute for Clinical Effectiveness and Health Policy (IECS)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.