[Intra-articular hyaluronic acid (viscosupplementation) for osteoarthritis]

Oubiña M, Bardach A, Pichon-Riviere A, Augustovski F, García Martí S, Alcaraz A, Ciapponi A.
Record ID 32018001529
Original Title: Ácido hialurónico intraarticular (viscosuplementación) en osteoartritis
Authors' recomendations: CONCLUSIONS Moderate-quality evidence suggests that intra-articular hyaluronic acid to treat knee osteoarthritis is more effective than placebo in terms of pain relief and functional improvement. Low-quality evidence suggests that the use of high molecular weight hyaluronic acid might have a considerable benefit in reducing pain compared to placebo. Moderate-quality evidence suggests that viscosupplementation with hyaluronic acid did no prove to be more beneficial than intra-articular corticosteroids, placebo or platelet-rich plasma when treating osteoarthritis of all joints. This evidence comes from clinical trials, which in general, did not exceed three-month treatment, in the context of chronic diseases. In addition, evidence should be interpreted with care since it comes, partially, from meta-analysis and network meta-analysis with high variability in its result estimators. Some clinical practice guidelines surveyed recommend using intra-articular hyaluronic acid only for knee osteoarthritis, where it would be another option for treating this condition, when other conservative treatments fail. Some United States health sponsors cover this technology for selected patients with knee osteoarthritis who have not shown response to oral drug therapy with non-steroidal anti-inflammatory drugs or paracetamol for three months. They do not cover this treatment for other joints, since they consider it experimental. No economic assessments carried out in Argentina, assessing this technology have been found.
Project Status: Completed
Year Published: 2019
URL for published report: https://www.iecs.org.ar/home-ets/
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Argentina
MeSH Terms
  • Osteoarthritis
  • Hyaluronic Acid
  • Viscosupplementation
Organisation Name: Institute for Clinical Effectiveness and Health Policy
Contact Address: Dr. Emilio Ravignani 2024, Buenos Aires - Argentina, C1414 CABA
Contact Name: info@iecs.org.ar
Contact Email: info@iecs.org.ar
Copyright: Institute for Clinical Effectiveness and Health Policy (IECS)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.