[Positron-emission tomography for breast cancer]

Perelli L, Gonzalez L, Pichon-Riviere A, Augustovski F, García Martí S, Alcaraz A, Bardach A, Ciapponi A.
Record ID 32018001528
Original Title: Tomografía por emisión de positrones en cáncer de mama
Authors' recomendations: CONCLUSIONS Moderate-quality evidence suggests that PET-CT has an adequate diagnostic performance in detecting metastasis when staging breast cancer, although it does not show a clear benefit when compared with other imaging methods such as computed tomography. Moderate-quality evidence suggests that PET-CT is worse in terms of diagnostic performance when compared with MRI for presurgical lymph node staging. As regards its use during neoadjuvant therapy, moderate-quality evidence suggests that PET-CT has a moderate correlation with achieving a complete disease response. Moderate-quality evidence suggests that PET-CT has a good diagnostic performance when suspecting relapse or recurrence. No evidence was found about PET-CT when assessing recurrence in asymptomatic patients, in post-treatment follow-up or treatment response monitoring of patients with advanced disease. No adequate quality evidence was found on the impact on clinical outcome of PET-CT use in any of the settings. None of the clinical practice guidelines surveyed recommend the routine use of PET-CT in breast cancer assessment, although there are heterogeneous recommendations for patients with suspected relapse or when staging locally advanced breast cancer. The public and health sponsors from high-income countries, except Australia and France cover PET-CT for breast cancer in specific clinical situations such as staging of locally advanced breast cancer or when assessing suspected relapse or recurrence. Most Latin American health sponsors surveyed do not mention the use of this technology, except for Uruguay, which covers it for specific situations. No economic studies have been found in Argentina, therefore its cost-effectiveness and budget impact are unknown.
Project Status: Completed
Year Published: 2019
URL for published report: https://www.iecs.org.ar/home-ets/
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Argentina
MeSH Terms
  • Breast Neoplasms
  • Positron Emission Tomography Computed Tomography
  • Positron-Emission Tomography
  • Diagnostic Imaging
Organisation Name: Institute for Clinical Effectiveness and Health Policy
Contact Address: Dr. Emilio Ravignani 2024, Buenos Aires - Argentina, C1414 CABA
Contact Name: info@iecs.org.ar
Contact Email: info@iecs.org.ar
Copyright: Institute for Clinical Effectiveness and Health Policy (IECS)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.