[Implantable cardiac defibrillator for primary prevention of sudden death]

Mengarelli C, Pichon-Riviere A, Augustovski F, García Martí S, Alcaraz A, Bardach A, Ciapponi A
Record ID 32018001506
Original Title: Cardiodesfibrilador implantable para la prevención primaria de la muerte súbita
Authors' recommendations: CONCLUSIONS High-quality evidence shows that the implantable cardiac defibrillator, as primary prevention strategy to avoid sudden death, reduces mortality for all causes and due to ventricular arrhythmia in three group of patients: patients with a history of myocardial infarction with an ejection fraction of less than 35% and sustained ventricular tachycardia; patients with a history of myocardial infarction and an ejection fraction of less than 30 %, and patients under 60 years old with dilated cardiomyopathy with heart failure. However, no benefit has been demonstrated in patients with recent ischemic heart disease. The clinical practice guidelines analyzed consider using implantable cardiac defibrillators for the above mentioned groups of patients. The United States, European, Argentinean and Brazilian health sponsors consulted cover this technology for the same indications. The cost-effectiveness studies conducted in Argentina and Brazil suggest that using implantable cardiac defibrillators would be cost-effective as primary prevention in the group of patients at high risk of ventricular arrhythmias and Functional Class III-IV heart failure; however, budget impact should be taken into account in view of the large number of patients who may be eligible for it.
Project Status: Completed
Year Published: 2018
URL for published report: https://www.iecs.org.ar/home-ets/
English language abstract: An English language summary is available
Publication Type: Not Assigned
Country: Argentina
MeSH Terms
  • Death, Sudden, Cardiac
  • Defibrillators, Implantable
  • Arrhythmias, Cardiac
Organisation Name: Institute for Clinical Effectiveness and Health Policy
Contact Address: Dr. Emilio Ravignani 2024, Buenos Aires - Argentina, C1414 CABA
Contact Name: info@iecs.org.ar
Contact Email: info@iecs.org.ar
Copyright: Institute for Clinical Effectiveness and Health Policy (IECS)
This is a bibliographic record of a published health technology assessment from a member of INAHTA or other HTA producer. No evaluation of the quality of this assessment has been made for the HTA database.